Typing competencies in Alzheimer's disease

摘要: BackgroundThe diagnostic work-up of Alzheimer Disease (AD) is complex, time-consuming, expensive, and quite demanding for the patients. Therefore, there a growing need simple non-invasive tools that add to ObjectivesThis paper investigates new method monitoring motor functions in AD using everyday interactions related writing with computer, i.c. executing copy task. MethodsAn experimental exploratory study was set up which carefully designed task presented three groups participants: young adults (n=20), cognitively healthy elderly (n=20) age-matched mild cognitive impairment (MCI) or dementia due (n=12). The consisted ten different sub-tasks specific bigram characteristics were manipulated. participants' typing behavior monitored keystroke logging. ResultsThe differed significantly from each other performing Typing speed gradually decreased age. Moreover, impaired performed slower on all subtasks expressed longer interkey intervals within targeted bigrams. Integrative multilevel modelling showed manipulated contributed model. ConclusionThis explorative shows potential relevance patients neurodegenerative brain disorders. It relates natural task, easy automatize. In comparison tasks it allows fine-grained measurements at an individual level combines aspects complex fine activities one A constructed proposed.A useful instrument patients.A level.A activities.