On the armament and appearances of human myeloid-derived suppressor cells.
作者： Isabel Poschke , Rolf Kiessling
DOI: 10.1016/J.CLIM.2012.06.003
关键词:
摘要: Abstract Myeloid-derived suppressor cells (MDSC) have frequently been observed in patients with cancer. This heterogeneous population of myeloid can exert potent suppression lymphocyte function and thereby poses a significant hurdle to natural or therapeutically induced anti-tumor immunity. On the other hand, MDSC is not yet well understood their role infection, inflammation autoimmune disease still puzzling. Understanding biology will provide tools necessary for therapeutic targeting this population, but also permit exploitation strong tolerogenic treatment inflammatory conditions prevention graft rejection.
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