A proteasome inhibitor prevents activation of NF-kappa B and stabilizes a newly phosphorylated form of I kappa B-alpha that is still bound to NF-kappa B.

作者： E.B. Traenckner , S. Wilk , P.A. Baeuerle

DOI: 10.1002/J.1460-2075.1994.TB06878.X

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摘要: … cells the kinase reaction did not release IKB-a from NF-KB, … The activation of the higher eukaryotic transcription factor NF-… TNF stimulation in the presence of PSI, its appearance did not …

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A proteasome inhibitor prevents activation of NF-kappa B and stabilizes a newly phosphorylated form of I kappa B-alpha that is still bound to NF-kappa B.

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A proteasome inhibitor prevents activation of NF-kappa B and stabilizes a newly phosphorylated form of I kappa B-alpha that is still bound to NF-kappa B.

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