Antibiotic susceptibility profile of Helicobacter pylori isolated from the dyspepsia patients in Tehran, Iran.

摘要: Background/Aim: Helicobacter pylori is an important pathogen for gastroduodenal diseases. Infection with H. can be limited by regimens of multiple antimicrobial agents. However, antibiotic resistance a leading cause treatment failure. The aim this study has been to determine the patterns strains isolated from gastric biopsies patients dyspepsia agar dilution method, in Tehran, Iran. Patients and Methods : isolates gastrointestinal diseases were evaluated susceptibility testing method. Susceptibility was performed commonly used antibiotics including clarithromycin, tetracycline, amoxicillin, metronidazole ciprofloxacin. Results: Among 92 dyspepsia, 42 patients. Seventeen (40.5%) resistant (MICs ≥ 8 μg/l), whereas one isolate (2.4%) amoxicillin ≤ 0. 5 μg/ml) ciprofloxacin 1μg/ml). rates other are recorded as follows: clarithromycin 6 (14.3 %), tetracycline 2 (4.8%). In cases, combined found. Conclusions: These data suggest that should among Iranian first-line therapy caution, association proton pump inhibitor more recommended.