Polymer-modified glassy carbon electrode for the electrochemical detection of quinine in human urine and pharmaceutical formulations

摘要: Glassy carbon electrode was modified by electropolymerization of 4-amino-3-hydroxynaphthalene sulfonic acid. Cyclic voltammetric study quinine showed higher current response at the compared to bare and activated glassy electrodes in pH 7.0 phosphate buffer solution. Under optimized conditions, a calibration curve obtained square wave voltammetry electrode. The linear relationship between peak concentration range 1.0 × 10−7 1.0 × 10−5 M I pa (in microamperes) = 6.26C micromolars) + 0.2997 (R 2 = 0.999). detection limit calculated (S/N = 3) 1.42 × 10−8 M, which is much lower than similar reports. method successfully applied for determination spiked human urine, pharmaceutical formulations recovery values >90 % were obtained.