Infectious Multiple Drug Resistance in the Enterobacteriaceae

摘要: Abstract : The antibiotic resistance gene of R plasmids which encodes for ampicillin resides upon a 3.7 x 3700000 dalton sequence DNA, TnA, can migrate (translocate) from plasmid to plasmid. translocation TnA occurs independently normal bacterial rec functions so that it permits rearrangement and recombination DNA species diverse backgrounds. insertion is mutagenic may have either polar effect or promotor depending its orientation insertion. Translocation sequences such as are powerful tools genetic research since into molecule provides readily identifiable physical marker. This feature has been exploited mark Ent K be used the construction vaccine strains. epidemiological implications discovery genes most significant. No longer should one simply think direct extension drug by transfer but rather an enormous reservoir available insert any species.