Cross-Disciplinary Genomics Approaches to Studying Emerging Fungal Infections.

摘要: Emerging fungal pathogens pose a serious, global and growing threat to food supply systems, wild ecosystems, human health. However, historic chronic underinvestment in their research has resulted limited understanding of epidemiology relative bacterial viral pathogens. Therefore, the untargeted nature genomics and, more widely, -omics approaches is particularly attractive addressing threats posed by illuminating biology these Typically, into plant, wildlife mycoses have been largely separated, with dialogue between disciplines. many serious facing world today common traits irrespective host species, such as plastic genomes; wide ranges; large population sizes an ability persist outside host. These commonalities mean that productively applied one sphere may also provide important insights others, where historically underutilised. In this review, we consider advances made fields plant pathology, medicine health progress linking genomes other datatypes sets; identify current barriers how are being underutilised each field; which methodologies it most crucial build capacity for near future.