Supervised exercise reduces cancer-related fatigue: a systematic review.

摘要: Question: Does supervised physical activity reduce cancer-related fatigue? Design: Systematic review with meta-analysis of randomised trials. Participants: People diagnosed any type cancer, without restriction to a particular stage diagnosis or treatment. Intervention: Supervised interventions (eg, aerobic, resistance and stretching exercise), defined as planned structured body movement causing an increase in energy expenditure, designed maintain enhance health-related outcomes, performed systematic frequency, intensity duration. Outcome measures: The primary outcome measure was fatigue. Secondary outcomes were functional wellbeing assessed using the Functional Assessment Cancer Therapy Fatigue Scale, European Organisation for Research Treatment Quality Life Questionnaire, Piper Schwartz Scale Multidimensional Inventory. Methodological quality, including risk bias studies, evaluated PEDro Scale. Results: Eleven studies involving 1530 participants included review. assessment quality showed mean score 6.5 (SD 1.1), indicating low overall bias. pooled effect on fatigue, calculated standardised difference (SMD) random-effects model, –1.69 (95% CI –2.99 –0.39). Beneficial reductions fatigue also found combined aerobic training supervision (SMD=–0.41, 95% –0.70 –0.13) (SMD=–0.67, –1.17 –0.17). Conclusion: These findings suggest that exercise regimens should be part rehabilitation programs people who have been cancer. Registration: PROSPERO CRD42013005803. [Meneses-Echavez JF, Gonzalez-Jimenez E, Ramirez-Velez R (2015) reduces fatigue: Journal Physiotherapy 61: 3–9]