COMPOSITION FOR REDUCING SENESCENCE OF CELL OR SUBJECT INCLUDING BRAF INHIBITOR AND USE THEREOF

Hiromitsu Nakauchi, Koji Eto, Naoya Takayama, Sou Nakamura, Novel method for producing differentiated cells ,(2010)

Christine Fritsch, Darrin Stuart, Tobi Nagel, Sauveur-Michel Maira, Susan Wee, Carlos Garcia-Echeverria, Combination of (a) a phosphoinositide 3-kinase inhibitor and (b) a modulator of ras/raf/mek pathway ,(2009)

Poulikos I. Poulikakos, Chao Zhang, Gideon Bollag, Kevan M. Shokat, Neal Rosen, RAF inhibitors transactivate RAF dimers and ERK signalling in cells with wild-type BRAF Nature. ,vol. 464, pp. 427- 430 ,(2010) , 10.1038/NATURE08902

Josette Carnahan, Pedro J. Beltran, Carol Babij, Quynh Le, Mark J. Rose, Steven Vonderfecht, Joseph L. Kim, Adrian L. Smith, Karthik Nagapudi, Martin A. Broome, Manory Fernando, Hue Kha, Brian Belmontes, Robert Radinsky, Richard Kendall, Teresa L. Burgess, Selective and Potent Raf Inhibitors Paradoxically Stimulate Normal Cell Proliferation and Tumor Growth Molecular Cancer Therapeutics. ,vol. 9, pp. 2399- 2410 ,(2010) , 10.1158/1535-7163.MCT-10-0181

Sonja J Heidorn, Carla Milagre, Steven Whittaker, Arnaud Nourry, Ion Niculescu-Duvas, Nathalie Dhomen, Jahan Hussain, Jorge S Reis-Filho, Caroline J Springer, Catrin Pritchard, Richard Marais, None, Kinase-Dead BRAF and Oncogenic RAS Cooperate to Drive Tumor Progression through CRAF Cell. ,vol. 140, pp. 209- 221 ,(2010) , 10.1016/J.CELL.2009.12.040

Jianli Dong, Treatment of cancer by simultaneous inhibition of b-raf and restoration or mimicry of p16 ink4a activity ,(2005)

Raul Rabadan, Brunangelo Falini, Enrico Tiacci, Hairy cell leukemia biomarkers and methods of using same ,(2012)

Levi A. Garraway, Cory M. Johannessen, Methods of diagnosing and treating cancer in patients having or developing resistance to a first cancer therapy ,(2011)

Ha Moon Kyung, Choi Hae Ri, Park Sang Chul, Cho Kyung A, RESTORATION OF CELLULAR SENESCENCE BY ALTERATION OF CELL TO MATRIX INTERACTION AND RESTORATION ,(2010)