β-Bungarotoxin inhibits a non-inactivating potassium current in guinea pig dorsal root ganglion neurones

摘要: Abstract β-Bungarotoxin (β-BuTx), at concentrations of 0.45–45 nmol/l, selectively reduced a portion the non-inactivating potassium current (I s k ) in dorsal root ganglion neurones guinea pig, measured by voltage clamp internally perfused cells. The average reduction I obtainable with β-BuTx was 34% and usually not completed within 20 min, but irreversible upon washing for min. I/V-characteristic blocked almost linear. It is suggested that blocks subtype channel.