Determination of lymphocyte immunophenotypic values for normal full-term cord blood.
作者： Michael P. Meyer , Rose Ann King , Gregory J. Naus , Darlene Motley
关键词:
摘要: Normal reference values for flow cytometric immunophenotypic lymphocyte markers cord blood (CB) were determined using sufficient numbers of subjects clinical laboratory use. Samples from 202 normal gestations processed by whole lysis and analyzed in the following combinations: CD14/45, CD4/3, CD8/3, CD45RA/4, CD29/4, CD56/3, Cd19/3, CD19/10. Thirty-five adult volunteers as controls. When compared to adults, CB showed increased relative percentages naive T-helper cells, B immature CD8+3-cells decreased T cytotoxic activated large granular lymphocytes (CD56+3+). Significant differences also found when samples stratified sex race. These results provide CB, demonstrate need determining separate standard significantly different patient populations, basis future investigation pathologic applications, insight into early immunologic development.
oup.com
sci-hub.se 参考文章(29)
Bryson Y, Plaeger-Marshall S, Giorgi Jv, Kobayashi Al, Hultin P, O'Rourke S, Kobayashi R, Bertolli J, Stiehm Er, Activation and differentiation antigens on T cells of healthy, at-risk, and HIV-infected children. Journal of Acquired Immune Deficiency Syndromes. ,vol. 6, pp. 984- 993 ,(1993)
DAVID A. BAKER, CHAUDHRY HAMEED, NERGESH TEJANI, JOANNE THOMAS, RAYMOND DATTWYLER, Lymphocyte subsets in the neonates of preeclamptic mothers American journal of reproductive immunology and microbiology : AJRIM. ,vol. 14, pp. 107- 109 ,(1987) , 10.1111/J.1600-0897.1987.TB00129.X
Thomas Denny, Ram Yogev, Rebecca Gelman, Christopher Skuza, James Oleske, Ellen Chadwick, Su-Chun Cheng, Edward Connor, Lymphocyte Subsets in Healthy Children During the First 5 Years of Life JAMA: The Journal of the American Medical Association. ,vol. 267, pp. 1484- 1488 ,(1992) , 10.1001/JAMA.1992.03480110060034
Herbert B. Slade, Jay H. Greenwood, Robert H. Beekman, Jerry L. Hudson, Savita Pahwa, Stanley A. Schwartz, Flow cytometric analysis of lymphocyte subpopulations in infants with congenital heart disease. Journal of Clinical Laboratory Analysis. ,vol. 3, pp. 14- 20 ,(1989) , 10.1002/JCLA.1860030105
Edward F. Srour, Tom Leemhuis, Laura Jenski, Robert Redmond, Jan Jansen, Cytolytic activity of human natural killer cell subpopulations isolated by four-color immunofluorescence flow cytometric cell sorting Cytometry. ,vol. 11, pp. 442- 446 ,(1990) , 10.1002/CYTO.990110316
R M Thomas, D C Linch, Identification of lymphocyte subsets in the newborn using a variety of monoclonal antibodies. Archives of Disease in Childhood. ,vol. 58, pp. 34- 38 ,(1983) , 10.1136/ADC.58.1.34
A. Durandy, C. Oury, C. Griscelli, Y. Dumez, J. F. Oury, R. Henrion, Prenatal testing for inherited immune deficiencies by fetal blood sampling. Prenatal Diagnosis. ,vol. 2, pp. 109- 113 ,(1982) , 10.1002/PD.1970020206
Doris Wiener, David T. Rowlands, Nancy Lowell, Shirish Shah, John Malone, Saul Lowitt, Multiparametric analysis of peripheral blood in the normal pediatric population by flow cytometry. Journal of Clinical Laboratory Analysis. ,vol. 4, pp. 175- 179 ,(1990) , 10.1002/JCLA.1860040305
KF Bradstock, A Kerr, P Grimsley, J Kirk, C Luxford, Phenotypic characterization of immature lymphoid cells in human umbilical cord blood. Immunology and Cell Biology. ,vol. 66, pp. 387- 394 ,(1988) , 10.1038/ICB.1988.50
P. De Paoli, S. Battistin, G.F. Santini, Age-related changes in human lymphocyte subsets: progressive reduction of the CD4 CD45R (suppressor inducer) population. Clinical Immunology and Immunopathology. ,vol. 48, pp. 290- 296 ,(1988) , 10.1016/0090-1229(88)90022-0