Processing speed, working memory, and IQ: a developmental model of cognitive deficits following cranial radiation therapy.

摘要: IQ decrements following cranial radiation therapy (CRT) for acute lymphoblastic leukemia (ALL) are most apparent years after treatment. The authors examined a developmental model delayed deficits by evaluating the relationship between processing speed, working memory, and in long-term survivors of childhood ALL (n = 27) compared with demographically matched controls 27). group treated CRT showed IQ, speed relative to controls. Differences were mediated differences memory. Processing did not fully account memory deficit group. Participants only chemotherapy similar as Data suggest that may underlie declines IQ.