作者: Hervé Bazin
DOI: 10.1007/978-1-4612-4826-2_18
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摘要: The first model of monoclonal antibody-secreting hybridomas, developed by Kohler and Milstein (1), was a mouse system. It can be considered eminently successful, most likely because its efficiency extreme stability. If it is so why develop another rodent model? There are, at least, three main reasons.