The effects of LASIK on the ocular surface.

作者: Renée Solomon , Erig D. Donnenfeld , Henry D. Perry

DOI: 10.1016/S1542-0124(12)70022-8

关键词:

摘要: Laser in situ keratomileusis (LASIK) can affect corneal sensation, aqueous tear production, wound healing, and the incidence of erosions. Virtually all patients experience dry eye at least transiently after LASIK. Because intact sensation drives denervation associated with LASIK procedure is most significant cause post-LASIK eye. To prevent symptomatic postoperative eye, it crucial to identify treat pre-existing before surgery. This review addresses pathophysiology management as well relationship between erosions, suggests intra- post-operative techniques minimize complications maximize stability ocular surface. Contraindications alternative refractive surgical procedures are discussed.

参考文章(76)
L J Müller, L Pels, B Willekens, G F Vrensen, B N Cardozo, Architecture of human corneal nerves. Investigative Ophthalmology & Visual Science. ,vol. 38, pp. 985- 994 ,(1997)
I K Gipson, A S Tisdale, S J Spurr-Michaud, Anchoring fibrils form a complex network in human and rabbit cornea Investigative Ophthalmology & Visual Science. ,vol. 28, pp. 212- 220 ,(1987)
J P Gilbard, K G Heyda, S R Rossi, D A Dartt, Stimulation of tear secretion by topical agents that increase cyclic nucleotide levels. Investigative Ophthalmology & Visual Science. ,vol. 31, pp. 1381- 1388 ,(1990)
J Gallar, C Belmonte, M Schmelz, M C Acosta, Measurement of corneal sensitivity to mechanical and chemical stimulation with a CO2 esthesiometer. Investigative Ophthalmology & Visual Science. ,vol. 40, pp. 513- 519 ,(1999)
C. Pholpramool, Secretory effect of prostaglandins on the rabbit lacrimal gland Prostaglandins and Medicine. ,vol. 3, pp. 185- 192 ,(1979) , 10.1016/0161-4630(79)90102-2
H Perry, CS Wu, E Donnenfeld, S Doshi, The Effect of Hinge Width on Corneal Sensation and Dry Eye Following LASIK Investigative Ophthalmology & Visual Science. ,vol. 43, pp. 2092- 2092 ,(2002)
Lucia Sobrin, Balakrishna Lokeshwar, Stephen C. Pflugfelder, Marie Selzer, Adolfo A. Afonso, Dagoberto C. Monroy, Tear fluid gelatinase B activity correlates with IL-1α concentration and fluorescein clearance in ocular rosacea Investigative Ophthalmology & Visual Science. ,vol. 40, pp. 2506- 2512 ,(1999)
Lucia Sobrin, Balakrishna L. Lokeshwar, Zuguo Liu, Marie G. Selzer, Stephen C. Pflugfelder, Abraham Solomon, Dagoberto C. Monroy, Regulation of MMP-9 activity in human tear fluid and corneal epithelial culture supernatant. Investigative Ophthalmology & Visual Science. ,vol. 41, pp. 1703- 1709 ,(2000)
L. J. Müller, L. Pels, G. F. J. M. Vrensen, Ultrastructural organization of human corneal nerves. Investigative Ophthalmology & Visual Science. ,vol. 37, pp. 476- 488 ,(1996)