Synthesis of indole thiazole compounds as ligands for the ah receptor
作者： Hector F. Deluca , Rafal R. Sicinski , Pawel K. Grzywacz
DOI:
关键词:
摘要: A method of synthesizing aromatic ketone compositions formula (I) comprising the step introducing a double bond into 5 membered ring 4,5-dihydro-1,3-azoles moiety (II) is disclosed. synthesis tetra hydro-1,3-azoles (XI) also
lens.org参考文章(33)
Atsushi Fujii, Kouzaburo Matsuzawa, Process of molding thermoplastic sheet by plug assist vacuum forming ,(1992)
William M. Westler, Hector F. Deluca, Richard E. Peterson, Raphal R. Sicinski, Jiasheng Song, Margaret Clagett-Dame, Preparations and use of an Ah receptor ligand, 2-(1′H-indole-3′-carbonyl)-thiazole-4-carboxylic acid methyl ester ,(2002)
A Rannug, U Rannug, H S Rosenkranz, L Winqvist, R Westerholm, E Agurell, A K Grafström, Certain photooxidized derivatives of tryptophan bind with very high affinity to the Ah receptor and are likely to be endogenous signal substances. Journal of Biological Chemistry. ,vol. 262, pp. 15422- 15427 ,(1987) , 10.1016/S0021-9258(18)47743-5
William G. Berrocal, James C. Benoit, Tamper-proof tie ,(2002)
Nwe Y. BaMaung, Megumi Kawai, Richard A. Craig, Jieyi Wang, 3-substituted indole angiogenesis inhibitors ,(2000)
R.-M. Liu, V. Vasiliou, H. Zhu, J.-L. Duh, M.W. Tabor, A. Puga, D.W. Nebert, M. Sainsbury, H.G. Shertzer, Regulation of [Ah] gene battery enzymes and glutathione levels by 5,10-dihydroindeno[1,2-b]indole in mouse hepatoma cell lines. Carcinogenesis. ,vol. 15, pp. 2347- 2352 ,(1994) , 10.1093/CARCIN/15.10.2347
Andrew J. Phillips, Yoshikazu Uto, Peter Wipf, Michael J. Reno, David R. Williams, Synthesis of Functionalized Oxazolines and Oxazoles with DAST and Deoxo-Fluor Organic Letters. ,vol. 2, pp. 1165- 1168 ,(2000) , 10.1021/OL005777B
J P Whitlock, Genetic and Molecular Aspects of 2,3,7,8-Tetra-Chlorodibenzo-P-Dioxin Action Annual Review of Pharmacology and Toxicology. ,vol. 30, pp. 251- 277 ,(1990) , 10.1146/ANNUREV.PA.30.040190.001343
Jun Adachi, Yoshitomo Mori, Saburo Matsui, Hidetaka Takigami, Junko Fujino, Hiroko Kitagawa, Charles A. Miller, Takaaki Kato, Kenichi Saeki, Tomonari Matsuda, Indirubin and Indigo Are Potent Aryl Hydrocarbon Receptor Ligands Present in Human Urine Journal of Biological Chemistry. ,vol. 276, pp. 31475- 31478 ,(2001) , 10.1074/JBC.C100238200
Vasilis Vasiliou, Howard G. Shertzer, Rui-Ming Liu, Malcolm Sainsbury, Daniel W. Nebert, Response of [Ah] battery genes to compounds that protect against menadione toxicity. Biochemical Pharmacology. ,vol. 50, pp. 1885- 1891 ,(1995) , 10.1016/0006-2952(95)02083-7