Biomedical Applications of Infrared and Raman Microscopy

摘要: INTRODUCTION The desire to analyze smaller and amounts of material is a common goal as we push the limits technology in trying solve chemical biochemical problems. In gas chromatography, fused-silica capillary columns (0.25 mm) have almost completely replaced larger-bore (1/4 1/8-inch) packed [1], detection are reduced liquid microbore with inner diameters 1 mm or less quickly replacing more traditional 4-mm [2]. Capillary electrophoresis likewise demonstrating advantages over conventional gel for many applications [3]. Mass spectrometers now capable detecting identifying materials picogram femtogram range [4]. Vibrational spectroscopic measurements which subject this review currently utilize experience optical microscopists configuring instrumentation extremely small specimens.