Cell growth inhibitory effect of cinnamic acid derivatives from propolis on human tumor cell lines.
作者： Yukihiro Akao , Hiroe Maruyama , Kenji Matsumoto , Kenji Ohguchi , Kumi Nishizawa
DOI: 10.1248/BPB.26.1057
关键词:
摘要: A cell growth inhibitory effect of drupanin and baccharin, ingredients propolis, was found in human cancer lines. These compounds induced apoptosis the cells characterized by morphological nucleosomal DNA fragmentation analysis. Their effects were less potent compared with that artepillin C, which is a known anticancer compound from propolis. Importantly, HL60 more sensitive to than Con A-stimulated peripheral blood lymphocytes, whereas potency C opposite drupanin.
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