Morphological Changes and Stress Redistribution in Osteoporotic Spine

摘要: Osteoporosis is characterized by a reduction in trabecular bone mass that results vertebral fracture when increased stresses secondary to loss exceed the breaking strength of vertebra. Non-uniform and adaptive changes cortical shell or bony endplate may compensate for, accentuate, mechanical effects loss. Finite element techniques can be used improve diagnostic assessment risk osteoporosis examining relationships among bone, shell, endplate. This paper reviews evidence for contributions endplate, posterior elements resistance body. It also presents 3D finite model lumbar motion segment calculate stress distributions normal osteoporotic vertebrae with variations density, thickness, thickness. The modeling shows takes 39% total axial load vertebrae, while share 27%, trabeculae 34%. With 50% mass, only 9% load, increase 59% 32%, respectively. A body shifts loads elements. These on 266% two-thirds has been lost. If both are lost, quadruple. maximum occurred superior anterolateral regions body, consistent observations wedge fractures women. Loss density reduced thickness more than seven times, significantly increasing failure. Cortical thinning alone, without will not reduce rigidity whole vertebra significantly, but significantly.