A prospective, descriptive study to identify the microbiological profile of chronic wounds in outpatients.

摘要: Indiscriminate use of antibiotics for infected chronic wounds is a global problem that may contribute to delayed healing and the development drug-resistant micro-organisms. A prospective, descriptive cohort study 50 male female outpatients (mean age 52.50 [+/- 14.84] years, range 18-90) with 52 was conducted investigate microbiological profile prevalence strains in nonhealing develop an evidence-based approach antibiotic therapy until drug sensitivity reports are available. Mean wound duration 8.23 (+/- 12.35) months (range 1.5-72), average size 29.70 37.83) cm, most patients had lower extremity diabetes mellitus (n = 20). Pus tissue samples were cultured tested. Most (45) contained single organism nine different genera isolated. Of those, 39 Gram-negative 11 Gram-positive (z 5.50, P 20 cm2 (z-test, <0.05). The presence two organisms more commonly observed postsurgical/traumatic wounds. Ten (10) out 55 pathogens (18.18%) isolated drug-resistant, including Pseudomonas (seven), methicillin-resistant Staphylococcus aureus (one), extended-spectrum beta lactamase (two--E. coli Citrobacter). (70%) obtained from persons mellitus. Overall piperacillin tazobactum combination high. Because monomicrobial flora high, if infection suspected, empiric should target prevalent flora. high rate MRSA discourage ulcers before obtaining culture results.