Deletion of IFN-γ reduces fumonisin-induced hepatotoxicity in mice via alterations in inflammatory cytokines and apoptotic factors
作者： Raghubir P. Sharma , Quanren He , Victor J. Johnson
DOI: 10.1089/10799900360520414
关键词:
摘要: Fumonisin B1 (FB1) produces species-specific and organ-specific toxicity, including equine leukoencephalomalacia, porcine pulmonary edema, hepatic or renal damage in other animals. FB1 causes i...
liebertonline.com参考文章(30)
Wentzel Ca Gelderblom, PG Thiel, TS Kellerman, JJ Van Der Lugt, Wfo Marasas, Jaw Coetzer, Leukoencephalomalacia in a horse induced by fumonisin B1 isolated from Fusarium moniliforme. Onderstepoort Journal of Veterinary Research. ,vol. 55, pp. 197- 203 ,(1988)
Hoshio Hiraide, Masuo Obinata, Ryuhei Okuyama, Shuhji Seki, Nobuaki Yanai, Haruhiko Takada, Katsuo Kumagai, Kouetsu Ogasawara, Masayuki Satoh, Kazuyoshi Takeda, Wataru Hashimoto, Involvement of NK1+ T Cells and Their IFN-γ Production in the Generalized Shwartzman Reaction Journal of Immunology. ,vol. 160, pp. 3522- 3527 ,(1998)
Yoichiro Iwakura, Kenji Sekikawa, Yoh Ichi Tagawa, Suppression of concanavalin A-induced hepatitis in IFN-gamma(-/-) mice, but not in TNF-alpha(-/-) mice: role for IFN-gamma in activating apoptosis of hepatocytes. Journal of Immunology. ,vol. 159, pp. 1418- 1428 ,(1997)
Ronald T. Riley, Kenneth A. Voss, William P. Norred, Charles W. Bacon, Filmore I. Meredith, Raghubir P. Sharma, Serine palmitoyltransferase inhibition reverses anti-proliferative effects of ceramide synthase inhibition in cultured renal cells and suppresses free sphingoid base accumulation in kidney of BALBc mice Environmental Toxicology and Pharmacology. ,vol. 7, pp. 109- 118 ,(1999) , 10.1016/S1382-6689(98)00047-7
Raghubir P. Sharma, Neetesh Bhandari, Quanren He, Ronald T. Riley, Kenneth A. Voss, Decreased fumonisin hepatotoxicity in mice with a targeted deletion of tumor necrosis factor receptor 1 Toxicology. ,vol. 159, pp. 69- 79 ,(2001) , 10.1016/S0300-483X(00)00405-4
N. Bhandari, C.C. Brown, R.P. Sharma, Fumonisin B1-induced localized activation of cytokine network in mouse liver. Food and Chemical Toxicology. ,vol. 40, pp. 1483- 1491 ,(2002) , 10.1016/S0278-6915(02)00075-3
P C Howard, R M Eppley, M E Stack, A Warbritton, K A Voss, R J Lorentzen, R M Kovach, T J Bucci, Fumonisin b1 carcinogenicity in a two-year feeding study using F344 rats and B6C3F1 mice. Environmental Health Perspectives. ,vol. 109, pp. 277- 282 ,(2001) , 10.1289/EHP.01109S2277
Neetesh Bhandari, Raghubir P, Sharma, Modulation of selected cell signaling genes in mouse liver by fumonisin B1. Chemico-Biological Interactions. ,vol. 139, pp. 317- 331 ,(2002) , 10.1016/S0009-2797(02)00008-X
Ronald T. Riley, Elaine Wang, Joseph J. Schroeder, Elizabeth R. Smith, Ronald D. Plattner, Hamed Abbas, Hwan-Soo Yoo, Alfred H. Merrill, Evidence for disruption of sphingolipid metabolism as a contributing factor in the toxicity and carcinogenicity of fumonisins Natural Toxins. ,vol. 4, pp. 3- 15 ,(1996) , 10.1002/19960401NT2
Troy A. Baudino, John L. Cleveland, The Max Network Gone Mad Molecular and Cellular Biology. ,vol. 21, pp. 691- 702 ,(2001) , 10.1128/MCB.21.3.691-702.2001