Oligophrenia in Combination with Congenital Ichthyosis and Spastic Disorders

摘要: This interesting clinical syndrome has been thoroughly studied in the county of Vasterbotton north Sweden. The picture is characterized by low-grade oligophrenia, pronounced ichthyosis, and evidence spastic diaplegia. A detailed genealogic geographic analysis suggested that this its origin a single gene mutation. rather exhaustive study was undertaken presented detail hope it would be value to research workers as analytic methods, pooling case material, genetic analysis. At time preparation very there had not previously described similar literature. However, within past two years, independent reports appearing neurologic pediatric journals dealing with cases type have reported both from United States England. It felt