Relationship Between Parathormone and Obesity-Linked Disorders.

作者: Sule Temizkan , Sevin Demir , Kadriye Aydin , Aysenur Ozderya , Hilal Toplu Ozturk

DOI: 10.1089/MET.2015.0062

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摘要: Abstract Background: In this study, we aimed to investigate whether high parathormone (PTH) levels in obese patients contribute the metabolic complications of obesity. Methods: A total 400 subjects aged 18–65 years were included. Anthropometric bioelectrical bioimpedance measures, blood tests, and 75 gram oral glucose tolerance test results evaluated. Results: Of subjects, 335 female. The mean age was 39 ± 10 years. median body mass index 36 (interquartile range 34–41). Subjects divided into quartiles according PTH levels. Groups included quartile 1 [n = 100, PTH; 42 (range 36–45)], 2 55 (51–59)], 3 73 (68–78)], 4 99 (89–125)]. Quartiles evaluated with a generalized linear model adjusted for age, sex, season recruitment. Systolic diastolic pressure, fasting glucose, homeostatic assessment-estimated insulin resistance, ...

参考文章(39)
Adriana J. van Ballegooijen, Bryan Kestenbaum, Michael C. Sachs, Ian H. de Boer, David S. Siscovick, Andrew N. Hoofnagle, Joachim H. Ix, Marjolein Visser, Ingeborg A. Brouwer, Association of 25-Hydroxyvitamin D and Parathyroid Hormone With Incident Hypertension Journal of the American College of Cardiology. ,vol. 63, pp. 1214- 1222 ,(2014) , 10.1016/J.JACC.2014.01.012
L B Houtkooper, T G Lohman, S B Going, W H Howell, Why bioelectrical impedance analysis should be used for estimating adiposity. The American Journal of Clinical Nutrition. ,vol. 64, ,(1996) , 10.1093/AJCN/64.3.436S
Monika H. E. Christensen, Simon N. Dankel, Yngve Nordbø, Jan Erik Varhaug, Bjørg Almås, Ernst A. Lien, Gunnar Mellgren, Primary Hyperparathyroidism Influences the Expression of Inflammatory and Metabolic Genes in Adipose Tissue PLoS ONE. ,vol. 6, pp. e20481- ,(2011) , 10.1371/JOURNAL.PONE.0020481
Jøran Hjelmesæth, Dag Hofsø, Erlend T Aasheim, Trond Jenssen, Johan Moan, Helle Hager, Jo Røislien, Jens Bollerslev, Parathyroid hormone, but not vitamin D, is associated with the metabolic syndrome in morbidly obese women and men: A cross-sectional study Cardiovascular Diabetology. ,vol. 8, pp. 7- 7 ,(2009) , 10.1186/1475-2840-8-7
Alfonso Bellia, Giorgia Marinoni, Monica D'Adamo, Valeria Guglielmi, Mauro Lombardo, Giulia Donadel, Paolo Gentileschi, Davide Lauro, Massimo Federici, Renato Lauro, Paolo Sbraccia, Parathyroid hormone and insulin resistance in distinct phenotypes of severe obesity: a cross-sectional analysis in middle-aged men and premenopausal women. The Journal of Clinical Endocrinology and Metabolism. ,vol. 97, pp. 4724- 4732 ,(2012) , 10.1210/JC.2012-2513
Evelyn Fischer, Anke Hannemann, Rainer Rettig, Wolfgang Lieb, Matthias Nauck, Anna Pallauf, Martin Bildingmaier, Felix Beuschlein, Henri Wallaschofski, Martin Reincke, A high aldosterone to renin ratio is associated with high serum parathyroid hormone concentrations in the general population. The Journal of Clinical Endocrinology and Metabolism. ,vol. 99, pp. 965- 971 ,(2014) , 10.1210/JC.2013-3214
Shusuke Yagi, Ken-ichi Aihara, Takeshi Kondo, Itsuro Endo, Junko Hotchi, Takayuki Ise, Takashi Iwase, Masashi Akaike, Toshio Matsumoto, Masataka Sata, High serum parathyroid hormone and calcium are risk factors for hypertension in Japanese patients Endocrine Journal. ,vol. 61, pp. 727- 733 ,(2014) , 10.1507/ENDOCRJ.EJ14-0004
W. H. Taylor, A. A. Khaleeli, Coincident diabetes mellitus and primary hyperparathyroidism. Diabetes-metabolism Research and Reviews. ,vol. 17, pp. 175- 180 ,(2001) , 10.1002/DMRR.199
A. J. van Ballegooijen, I. Reinders, M. Visser, J. M. Dekker, G. Nijpels, C. D. A. Stehouwer, S. Pilz, I. A. Brouwer, Serum Parathyroid Hormone in Relation to All-Cause and Cardiovascular Mortality: The Hoorn Study The Journal of Clinical Endocrinology and Metabolism. ,vol. 98, ,(2013) , 10.1210/JC.2012-4007