Prospective Evaluation of Positron Emission Tomography in the Preoperative Staging of Esophageal Carcinoma

作者: Werner Kneist , Mathias Schreckenberger , Peter Bartenstein , Christian Menzel , Katja Oberholzer

DOI: 10.1001/ARCHSURG.139.10.1043

关键词:

摘要: Hypothesis Positron emission tomography (PET) is a useful tool in the selection of patients with esophageal cancer who may not benefit from resection. Design Case series. Setting Tertiary care hospital. Patients Eighty-one newly diagnosed underwent PET and computer (CT) chest abdomen (and neck 45 patients) within days were included. Main Outcome Measures We calculated sensitivity specificity detecting metastatic sites on basis 31 histologically verified lesions. In addition to results obtained CT, information provided by was evaluated view choice management strategies. Results The findings had higher (89% vs 11%) but lower (38% 63%) than CT detection sites. showed greater agreement histopathological did results. 8 (10%), detected distant metastases that identified CT. 4 (5%), bone only, all these other locations Although led upstaging (M1) 2 (2%), it enable exclusion Conclusions Preoperative characterized accuracy previously Therefore, lead change indication for esophagectomy. An increase combined use new indications this staging procedure.

参考文章(24)
P. Pokieser, M. Memarsadeghi, M. Danzer, R. Prokesch, B. Partik, E. Wenzl, Staging von Karzinomen des oberen Gastrointestinaltraktes Standortbestimmung der Bildgebung Radiologe. ,vol. 39, pp. 555- 561 ,(1999) , 10.1007/S001170050550
V Vilgrain, D Mompoint, L Palazzo, Y Menu, B Gayet, P Ollier, H Nahum, F Fekete, Staging of esophageal carcinoma: comparison of results with endoscopic sonography and CT. American Journal of Roentgenology. ,vol. 155, pp. 277- 281 ,(1990) , 10.2214/AJR.155.2.2115251
Mark I Block, G.Alexander Patterson, R.Sudhir Sundaresan, Marci S Bailey, Fidelma L Flanagan, Farrokh Dehdashti, Barry A Siegel, Joel D Cooper, Improvement in staging of esophageal cancer with the addition of positron emission tomography The Annals of Thoracic Surgery. ,vol. 64, pp. 770- 777 ,(1997) , 10.1016/S0003-4975(97)00619-X
Sonia J Wakelin, Chris Deans, Trevor J Crofts, Paul L Allan, John N Plevris, Simon Paterson-Brown, A comparison of computerised tomography, laparoscopic ultrasound and endoscopic ultrasound in the preoperative staging of oesophago-gastric carcinoma European Journal of Radiology. ,vol. 41, pp. 161- 167 ,(2002) , 10.1016/S0720-048X(01)00418-1
Michael B Wallace, Paul J Nietert, Craig Earle, Mark J Krasna, Robert H Hawes, Brenda J Hoffman, Carolyn E Reed, An analysis of multiple staging management strategies for carcinoma of the esophagus: computed tomography, endoscopic ultrasound, positron emission tomography, and thoracoscopy/laparoscopy The Annals of Thoracic Surgery. ,vol. 74, pp. 1026- 1032 ,(2002) , 10.1016/S0003-4975(02)03875-4
S.C. Rankin, H. Taylor, G.J.R. Cook, R. Mason, Computed tomography and positron emission tomography in the pre-operative staging of oesophageal carcinoma. Clinical Radiology. ,vol. 53, pp. 659- 665 ,(1998) , 10.1016/S0009-9260(98)80292-4
Sherry M Wren, Pascal Stijns, Sandy Srinivas, Positron Emission Tomography in the Initial Staging of Esophageal Cancer Archives of Surgery. ,vol. 137, pp. 1001- 1006 ,(2002) , 10.1001/ARCHSURG.137.9.1001
Jari V. Räsänen, Eero I. T. Sihvo, M. Juhani Knuuti, Heikki R. I. Minn, Markku E. S. Luostarinen, Pekka Laippala, Tapio Viljanen, Jarmo A. Salo, Prospective Analysis of Accuracy of Positron Emission Tomography, Computed Tomography, and Endoscopic Ultrasonography in Staging of Adenocarcinoma of the Esophagus and the Esophagogastric Junction Annals of Surgical Oncology. ,vol. 10, pp. 954- 960 ,(2003) , 10.1245/ASO.2003.12.002
F L Flanagan, F Dehdashti, B A Siegel, D D Trask, S R Sundaresan, G A Patterson, J D Cooper, Staging of esophageal cancer with 18F-fluorodeoxyglucose positron emission tomography American Journal of Roentgenology. ,vol. 168, pp. 417- 424 ,(1997) , 10.2214/AJR.168.2.9016218