Graphics Processing Unit-Based Ultrahigh Speed Real-Time Fourier Domain Optical Coherence Tomography

摘要: This paper describes a series of novel graphics processing unit (GPU)-based image reconstruction and visualization methods that we developed for realizing ultrahigh speed, real-time Fourier domain optical coherence tomography (FD-OCT). Several GPU-based algorithms including high-speed linear/cubic interpolation, gridding-based nonuniform fast transform (NUFFT), numerical dispersion compensation, multi-GPU implementation were to improve the point-spread function, SNR roll-off, stability system. Full-range complex-conjugate-free FD-OCT was also implemented on GPU architecture double imaging range SNR. The maximum speed $>$ 3 Gigavoxels/s ( 6 Mega-A-scans/s 1024-pixel FD-OCT) achieved using latest module from NVIDIA. volume rendering enabled four-dimensional (4-D), i.e., 3-D + time, imaging, 5 volume/s 4-D system demonstrated via in vivo tissue imaging. These technologies highly effective circumventing well-known bottlenecks existing among current systems could open door realize interventional OCT applications guiding microsurgery.