Recombination and Gene Flux Caused by Gene Conversion and Crossing Over in Inversion Heterokaryotypes

摘要: A theoretical analysis of the effects inversions on recombination and gene flux between arrangements caused by conversion crossing over was carried out. Two different mathematical models were used: Poisson model (without interference) Counting (with interference). The main results are as follows. (1) Recombination highly site-dependent both inside outside inverted regions. (2) Crossing overwhelms a cause in large inversions, while becomes relatively significant short regions around breakpoints. (3) Under rate two markers depends strongly position along segment. equally spaced central part segment have less than if they more extreme position. (4) Inversions affect rates uninverted chromosome. increases distal decreases proximal These provide an explanation for number observations reported literature. Because ubiquitous evolutionary history many Drosophila species, expected to influence DNA variation patterns.