作者: ANGELO C. NOTIDES
DOI: 10.1016/B978-0-12-526302-3.50007-1
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摘要: Publisher Summary The chapter discusses conformational forms of the estrogen receptor. transformation or activation receptor is an estradiol-dependent and temperature-dependent change modifying receptor's intrinsic activity sedimentation characteristics. estrogen-induced may be attributed to a in one more properties 4S estrogen-binding protein (EBP): (1) shape, producing form with hydrodynamic that permit faster sedimentation, (2) partial specific volume density, for example, by phosphorylation dissociation lipid moiety, (3) mass, association another macromolecule. A any these could provoked binding estradiol independent action enzyme. 5S activated transformed formed macromolecule, independently