Essential oil composition and antimicrobial activity of Artemisia dracunculus L. var. qinghaiensis Y. R. Ling (Asteraceae) from Qinghai-Tibet Plateau

摘要: Abstract Many plant species that occur at the high-altitudes such as Qinghai-Tibet Plateau (QTP) under extreme climate conditions have potential medicinal functions. To explore use of plants, we extracted essential oil from Artemisia dracunculus var. qinghaiensis Y. R. Ling collected QTP flower-buds stage (0.67% v/w) by hydro-distillation method. The chemical compositions and antimicrobial activity were determined using gas chromatography/mass spectrometry (GC/MS) agar disk-diffusion methods, respectively. Thirty-seven compounds accounting for 60.88% total detected components, with a high proportion monoterpenes (42.12%) identified in oil. Of these, sabinene (19.19%), β-terpinene (8.94%), terpinen-4-ol (3.83%), α-pinene (3.08%) major compounds. showed inhibitory against seven microbial strains (Staphylococcus aureus, Micrococcus luteus, Bacillus subtilis, Klebsiella pneumoniae, Pseudomonas aeruginosa, Salmonella paratyphi, Saccharomyces cerevisiae) minimum concentrations (MICs) 1.25–5.0 μl/ml. Our results suggest A. can be used biomedical resource.