Stroke in an early adolescent with systemic lupus erythematosus and coexistent antiphospholipid antibodies.

摘要: Thromboembolic events in systemic lupus erythematosus (SLE) are an occasional but significant occurrence. Cerebrovascular disease adults with SLE has been well described.1-4 Antiphospholipid antibodies, such as anticoagulant, immunoglobulin directed against the platelet phospholipid component of prothrombin activator complex, and false-positive serologic tests for syphilis, which detect reaginic antibodies that react purified beef cardiolipin substrate these assays, have reported a long time association events.5-9 More recently, development assay anticardiolipin immunoglobulins phosphodiester group negatively charged phospholipids, led to wider exploration this subset antiphospholipid their relation thrombosis.10,11