Compositions comprising bone marrow cells, demineralized bone matrix and rtg polymers for use in the induction of bone and cartilage formation

摘要: A composition comprising bone marrow cells (BMC) and demineralized matrix (DBM) or tooth (DTM), together with a reverse thermogelating polymer (RTG), optionally further morphogenetic protein/s (BMP) and/or other active agents, particularly for use in the transplantation of mesenchymal progenitor into joint cranio-facial-maxillary bone, alveolar maxilla mandibula, spine, pelvis long bones, construction reconstruction any extra skeletal including mechanical biological support artificial implants to restoring enhancing formation new hyaline cartilage subchondral structure.The BMC-DBM-RTG invention may be used treatment hereditary acquired disorders, primary secondary malignant metabolic diseases, lesions caused by trauma, infection, inflammatory process due unknown autoimmune etiology, conditions involving deformities Paget's disease. The correction complex fractures, replacement plastic sexual surgery, joints, musculoskeletal implants, implants. treating damaged joints degenerative arthropathy associated malformation dysfunction cartilage, subchondral, part bone.A kit is provided performing joint, maxillary mandibular bony structure mammal,