Gene variants predisposing to SIDS: current knowledge
作者： Siri H. Opdal , Torleiv O. Rognum
DOI: 10.1007/S12024-010-9182-9
关键词:
摘要: Genetic risk factors play a role in sudden unexpected infant death; either as cause of death, such cases with medium-chain acyl-coenzyme A dehydrogenase deficiency and cardiac arrest due to long QT syndrome, or predisposing for death syndrome (SIDS). Most likely genetic predisposition SIDS represent polygenic inheritance pattern leading when combined other factors, vulnerable developmental stage the central nervous system and/or immune system, addition environmental common cold prone sleeping position. Genes involved regulation function, serotonergic network brain function development have so far emerged most important respect SIDS. The purpose present paper is survey current knowledge on possible contributions.
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