The immunologic and genetic basis of psoriasis.
作者： Brian J. Nickoloff
DOI: 10.1001/ARCHDERM.135.9.1104
关键词:
摘要: In 1991, a comprehensive review was published highlighting the importance of cytokines in immunopathogenesis psoriasis. 1 Since then, many advances have been made regarding critical role for pathogenic T cells as causing this common and enigmatic skin disease. While epidermal keratinocytes are clearly involved participants establishment appropriate cytokine milieu presented earlier, more recent data point to lymphocytes triggering chain reaction cellular molecular networks that culminate formation psoriatic plaque. review, 3 major topics will be addressed.
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