Structure and function of the Golgi organelle in parasitic protists

摘要: At least three aspects make study of endomembrane systems parasitic protists scientifically important. First, unicellular parasites are promising objects to clarify Golgi functions, as well mechanisms intracellular transport because they possess essentially reduced secretory machinery, often coupled with hypertrophied secretion certain proteins. A comparative molecular analysis their compact genomes is helpful in determining the minimal set genes for and functions. In addition, small cell size many facilitates morphological analysis, particularly, three-dimensional reconstruction compartment (Beznoussenko et al. 2007; Cooke 2004; Joiner Roos 2002; Lujan Touz 2003; Overath Engstler Plattner 1993). Second, knowledge about specific function system pathogenic could be development pharmaceutical drugs. Third, ancestral nature trafficking depends on topology rooting eukaryotic tree (Richards Cavalier-Smith 2005). Thus, by reconstructing states help understanding origin evolution not only system, but also per se.