It's not just a phase: crystallization and X-ray structure determination of bacteriorhodopsin in lipidic cubic phases

作者: Eric Gouaux

DOI: 10.1016/S0969-2126(98)00002-1

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摘要: Utilization of lipidic cubic phases in the crystallization bacteriorhodopsin (bR) has yielded long sought after crystals that diffract X-rays to 2 A resolution. The resulting structure provides new information on protein conformation and mechanism proton translocation. Crystallization bR via may be a harbinger membrane strategies.

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