The Cockayne syndrome: an evaluation of hypertension and studies of renal pathology.

摘要: Three children with renal disease, hypertension, and the Cockayne syndrome were evaluated. All patients had severe hypertension; peripheral vein renin was elevated in two patients. Renal biopsy specimens from studied by light microscopy, electron immunofluoresence. Immunohistologic studies demonstrated deposits of immunoglobulin complement vessels glomeruli first patient; seen third patient. Also electron-dense glomerular basement membrane Circulating immune complexes detected Raji cell Clq binding techniques this child as well. Both hypertension disease are frequent complications syndrome.