Dynamic Coordination Chemistry Enables Free Directional Printing of Biopolymer Hydrogel

摘要: Three-dimensional (3D) printing is a promising technology to develop customized biomaterials in regenerative medicine. However, for the majority of printable (bioinks) there always compromise between excellent printability fluids and good mechanical properties solids. soft materials based on transition from fluid gel state challenging because difficulties control such as well maintain uniform conditions three-dimensionally. To solve these challenges, facile chemical strategy development novel hydrogel bioink with shear-thinning self-healing dynamic metal–ligand coordination bonds presented. The noncovalent cross-linking allows easy extrusion reservoir without changing its bulk properties. can avoid deformation collapse using omnidirectional embedding into support bath sharing same ...