Comparative therapeutic efficacy of remdesivir and combination lopinavir, ritonavir, and interferon beta against MERS-CoV.

作者: Timothy P. Sheahan , Amy C. Sims , Sarah R. Leist , Alexandra Schäfer , John Won

DOI: 10.1038/S41467-019-13940-6

关键词:

摘要: Middle East respiratory syndrome coronavirus (MERS-CoV) is the causative agent of a severe respiratory disease associated with more than 2468 human infections and over 851 …

参考文章(53)
Vineet D. Menachery, Lisa E. Gralinski, Ralph S. Baric, Martin T. Ferris, New Metrics for Evaluating Viral Respiratory Pathogenesis PLOS ONE. ,vol. 10, pp. e0131451- ,(2015) , 10.1371/JOURNAL.PONE.0131451
JS Lambert, LJ Else, V Jackson, J Breiden, S Gibbons, L Dickinson, DJ Back, M Brennan, EO Connor, N Boyle, C Fleming, S Coulter-Smith, SH Khoo, Therapeutic drug monitoring of lopinavir/ritonavir in pregnancy. Hiv Medicine. ,vol. 12, pp. 166- 173 ,(2011) , 10.1111/J.1468-1293.2010.00865.X
Reed F. Johnson, Laura E. Via, Mia R. Kumar, Joseph P. Cornish, Srikanth Yellayi, Louis Huzella, Elena Postnikova, Nicholas Oberlander, Christopher Bartos, Britini L. Ork, Steven Mazur, Cindy Allan, Michael R. Holbrook, Jeffrey Solomon, Joshua C. Johnson, James Pickel, Lisa E. Hensley, Peter B. Jahrling, Intratracheal exposure of common marmosets to MERS-CoV Jordan-n3/2012 or MERS-CoV EMC/2012 isolates does not result in lethal disease. Virology. ,vol. 485, pp. 422- 430 ,(2015) , 10.1016/J.VIROL.2015.07.013
Rudragouda Channappanavar, Lu Lu, Shuai Xia, Lanying Du, David K. Meyerholz, Stanley Perlman, Shibo Jiang, Protective Effect of Intranasal Regimens Containing Peptidic Middle East Respiratory Syndrome Coronavirus Fusion Inhibitor Against MERS-CoV Infection The Journal of Infectious Diseases. ,vol. 212, pp. 1894- 1903 ,(2015) , 10.1093/INFDIS/JIV325
Jasper Fuk-Woo Chan, Yanfeng Yao, Man-Lung Yeung, Wei Deng, Linlin Bao, Lilong Jia, Fengdi Li, Chong Xiao, Hong Gao, Pin Yu, Jian-Piao Cai, Hin Chu, Jie Zhou, Honglin Chen, Chuan Qin, Kwok-Yung Yuen, Treatment With Lopinavir/Ritonavir or Interferon-β1b Improves Outcome of MERS-CoV Infection in a Nonhuman Primate Model of Common Marmoset The Journal of Infectious Diseases. ,vol. 212, pp. 1904- 1913 ,(2015) , 10.1093/INFDIS/JIV392
T. Scobey, B. L. Yount, A. C. Sims, E. F. Donaldson, S. S. Agnihothram, V. D. Menachery, R. L. Graham, J. Swanstrom, P. F. Bove, J. D. Kim, S. Grego, S. H. Randell, R. S. Baric, Reverse genetics with a full-length infectious cDNA of the Middle East respiratory syndrome coronavirus Proceedings of the National Academy of Sciences. ,vol. 110, pp. 16157- 16162 ,(2013) , 10.1073/PNAS.1311542110
Gustavo Matute-Bello, Gregory Downey, Bethany B Moore, Steve D Groshong, Michael A Matthay, Arthur S Slutsky, Wolfgang M Kuebler, None, An Official American Thoracic Society Workshop Report: Features and Measurements of Experimental Acute Lung Injury in Animals American Journal of Respiratory Cell and Molecular Biology. ,vol. 44, pp. 725- 738 ,(2011) , 10.1165/RCMB.2009-0210ST
Xing-Yi Ge, Jia-Lu Li, Xing-Lou Yang, Aleksei A. Chmura, Guangjian Zhu, Jonathan H. Epstein, Jonna K. Mazet, Ben Hu, Wei Zhang, Cheng Peng, Yu-Ji Zhang, Chu-Ming Luo, Bing Tan, Ning Wang, Yan Zhu, Gary Crameri, Shu-Yi Zhang, Lin-Fa Wang, Peter Daszak, Zheng-Li Shi, Isolation and characterization of a bat SARS-like coronavirus that uses the ACE2 receptor Nature. ,vol. 503, pp. 535- 538 ,(2013) , 10.1038/NATURE12711
Darryl Falzarano, Emmie de Wit, Friederike Feldmann, Angela L. Rasmussen, Atsushi Okumura, Xinxia Peng, Matthew J. Thomas, Neeltje van Doremalen, Elaine Haddock, Lee Nagy, Rachel LaCasse, Tingting Liu, Jiang Zhu, Jason S. McLellan, Dana P. Scott, Michael G. Katze, Heinz Feldmann, Vincent J. Munster, Infection with MERS-CoV Causes Lethal Pneumonia in the Common Marmoset PLoS Pathogens. ,vol. 10, pp. e1004250- ,(2014) , 10.1371/JOURNAL.PPAT.1004250
Masaya Fukushi, Tateki Ito, Teruaki Oka, Toshio Kitazawa, Tohru Miyoshi-Akiyama, Teruo Kirikae, Makoto Yamashita, Koichiro Kudo, Serial Histopathological Examination of the Lungs of Mice Infected with Influenza A Virus PR8 Strain PLoS ONE. ,vol. 6, pp. e21207- ,(2011) , 10.1371/JOURNAL.PONE.0021207