Antidépresseurs et tamoxifène : une interaction méconnue

作者: Mélanie Moulis , Charles Khouri , Michel Mallaret

DOI: 10.2515/THERAPIE/2013077

关键词:

摘要: The interaction between tamoxifen and antidepressants which are CYP2D6 inhibitors is unknown, as shown in our study these prescribed to 11% of women receiving tamoxifen.

参考文章(8)
Solai Elango Damodaran, Suresh Chandra Pradhan, Gurusamy Umamaheswaran, Dharanipragada Kadambari, K. Sathyanarayana Reddy, Chandrasekaran Adithan, Genetic polymorphisms of CYP2D6 increase the risk for recurrence of breast cancer in patients receiving tamoxifen as an adjuvant therapy Cancer Chemotherapy and Pharmacology. ,vol. 70, pp. 75- 81 ,(2012) , 10.1007/S00280-012-1891-1
Lisette Binkhorst, Ron H. J. Mathijssen, Myrthe P. P. van Herk-Sukel, Marjolein Bannink, Agnes Jager, Erik A. C. Wiemer, Teun van Gelder, Unjustified prescribing of CYP2D6 inhibiting SSRIs in women treated with tamoxifen Breast Cancer Research and Treatment. ,vol. 139, pp. 923- 929 ,(2013) , 10.1007/S10549-013-2585-Z
C. M Kelly, D. N Juurlink, T. Gomes, M. Duong-Hua, K. I Pritchard, P. C Austin, L. F Paszat, Selective serotonin reuptake inhibitors and breast cancer mortality in women receiving tamoxifen: a population based cohort study BMJ. ,vol. 340, ,(2010) , 10.1136/BMJ.C693
Julie Eve Desmarais, Karl J. Looper, Interactions between tamoxifen and antidepressants via cytochrome P450 2D6. The Journal of Clinical Psychiatry. ,vol. 70, pp. 1688- 1697 ,(2009) , 10.4088/JCP.08R04856BLU
Madhu S. Singh, Prudence A. Francis, Michael Michael, Tamoxifen, cytochrome P450 genes and breast cancer clinical outcomes The Breast. ,vol. 20, pp. 111- 118 ,(2011) , 10.1016/J.BREAST.2010.11.003
H. Kim Crewe, Lisa M. Notley, Rebecca M. Wunsch, Martin S. Lennard, Elizabeth M. J. Gillam, Metabolism of tamoxifen by recombinant human cytochrome P450 enzymes: formation of the 4-hydroxy, 4'-hydroxy and N-desmethyl metabolites and isomerization of trans-4-hydroxytamoxifen. Drug Metabolism and Disposition. ,vol. 30, pp. 869- 874 ,(2002) , 10.1124/DMD.30.8.869
Vered Stearns, Michael D Johnson, James M Rae, Alan Morocho, Antonella Novielli, Pankaj Bhargava, Daniel F Hayes, Zeruesenay Desta, David A Flockhart, Active Tamoxifen Metabolite Plasma Concentrations After Coadministration of Tamoxifen and the Selective Serotonin Reuptake Inhibitor Paroxetine Journal of the National Cancer Institute. ,vol. 95, pp. 1758- 1764 ,(2003) , 10.1093/JNCI/DJG108