Synthesis of fluorinated oxygen- and sulfur-containing heteroaromatics

摘要: Abstract The incorporation of fluorine into a target molecule may have considerable impact on its reactivity, selectivity, biological activity and physical properties. This is especially true in medicinal chemistry where often employed as bioisostere hydrogen many important drug compounds also feature heteroaromatic rings. work complements existing reviews the synthesis fluorinated, aromatic heterocycles, with focus less common oxygen-containing heteroaromatics well their sulfur-based analogues.