Somato-sensory evoked responses in patients with unilateral cerebral lesions

摘要: Abstract The primary purpose of this study was to test the hypothesis that early and late somatic evoked response (SER) components are mediated, respectively, by activity short latency lemniscal pathway extra-lemniscal, bilaterally projecting reticular non-specific thalamo-cortical pathwats. scalp-recorded SER examined in seventeen patients, fourteen whom had unilateral cerebral lesions involved parietal cortex resulted sensory deficit. In those patients with severe loss, all were markedly reduced or abolished over both hemispheres when affected side stimulated. Patients mild moderate impairment exhibited either a normal generalized attenuation Stimulation relatively responses patients. These results do not favor dual projection hypothesis. Our others discussed consistent conclusion entire contralateral is result mediated solely medial system. Long ipsilateral apparently subsequent activation hemisphere via an inter-hemispheric pathway, possibly involving corpus callosum. agreement earlier studies, good correlation betweenm clinical loss alteration provides basis for future clincial use technique.