Antimicrobial Activity of Copper Alloys Against Invasive Multidrug-Resistant Nosocomial Pathogens.
作者： Ozgen Koseoglu Eser , Alper Ergin , Gulsen Hascelik
DOI: 10.1007/S00284-015-0840-8
关键词:
摘要: The emergence and spread of antibiotic resistance demanded novel approaches for the prevention nosocomial infections, metallic copper surfaces have been suggested as an alternative control multidrug-resistant (MDR) bacteria in hospital environment. This study aimed to evaluate antimicrobial activity material invasive MDR pathogens isolated over time, comparison stainless steel. Clinical isolates methicillin-resistant Staphylococcus aureus (MRSA) (n:4), OXA-23 OXA-58 positive, Acinetobacter baumannii (n:6) Pseudomonas aeruginosa (n:4) were evaluated. coupons containing 99 % a brass alloy 63 % was assessed against All materials demonstrated statistically significant differences within each other logarithmic reduction microorganisms. Among three materials, highest microorganisms seen least result especially 0, 2, 4 h (P = 0.05). showed bactericidal effect at less than 1 h MRSA 2 h P. aeruginosa. 24 h strains only. Stainless steel exhibited bacteriostatic after 6 h reduced number used significantly, produced more effective copper. use could aid reducing concentration bacteria, on hard
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