Palladium catalysed synthesis of spiroindolines.
作者： Ronald Grigg , Paul Fretwell , Clive Meerholtz , Visuvanathar Sridharan
DOI: 10.1016/S0040-4020(01)80760-2
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摘要: Abstract A series of palladiun catalysed consecutive bis(5-exo trig)-, 5-exo trig-6-exo trig-, and trig-7-endo trig-cyclisations via an alkene relay onto benzene or a wide range heterocycles (pyrrole.furan, thiophen. indole, pyridine, pyridones) generates 5,5-, 5,6- 5,7-spiroindolines in good yield.
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