Cholesterol and Coronary Heart Disease

摘要: Recent clinical trials have demonstrated that reductions of serum low-density lipoprotein (LDL) levels substantially decrease the risk for coronary heart disease. These confirm other lines evidence high LDL are a critical atherogenic factor. Aggressive lowering in high-risk patients promises to significantly reduce morbidity and mortality from disease first third 21st century. However, several additional measures will be required marginalize Other abnormalities factors, eg, cigarette smoking, hypertension, diabetes mellitus, must controlled obtain full benefit LDL-lowering therapy. Moreover, health care delivery system reorganized put more emphasis on prevention. Although much can achieved through application current knowledge prevention efforts, further advances new research remove as major cause death United States. Arch Intern Med. 1997;157:1177-1184