Human telomerase inhibitors from microbial source
作者： Kalarikkal Gopikrishnan Kiran , Muthusamy Palaniswamy , Jayaraman Angayarkanni
DOI: 10.1007/S11274-015-1893-3
关键词:
摘要: Telomerase enzyme inhibitors have gained attention of scientific field due to the specificity action telomerase based therapies. Some good combinatorial with certain DNA damaging drugs. Natural compounds isolated from microbes provide a new scope screening and large scale production inhibitors. This review emphasizes biochemistry mode different types microbial sources. Also elaborates on classification their in cancer cells.
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sci-hub.se 参考文章(97)
D. Tresselt, K. Eckardt, W. Ihn, Antibiotika aus actinomyceten. Zur chemischen konstitution des antibiotikums griseorhodin A Tetrahedron. ,vol. 34, pp. 2693- 2699 ,(1978) , 10.1016/0040-4020(78)88406-3
Hélène LaBranche, Sophie Dupuis, Yaacov Ben-David, Maria-Rosa Bani, Raymund J. Wellinger, Benoit Chabot, Telomere elongation by hnRNP A1 and a derivative that interacts with telomeric repeats and telomerase Nature Genetics. ,vol. 19, pp. 199- 202 ,(1998) , 10.1038/575
William C. Hahn, Christopher M. Counter, Ante S. Lundberg, Roderick L. Beijersbergen, Mary W. Brooks, Robert A. Weinberg, Creation of human tumour cells with defined genetic elements Nature. ,vol. 400, pp. 464- 468 ,(1999) , 10.1038/22780
Constantine S. Mitsiades, Teru Hideshima, Nicholas Mitsiades, Nikhil C. Munshi, Toshiaki Hayashi, Dharminder Chauhan, Kenneth C. Anderson, Paul Richardson, Yu-Tzu Tai, Masaharu Akiyama, Cytokines Modulate Telomerase Activity in a Human Multiple Myeloma Cell Line Cancer Research. ,vol. 62, pp. 3876- 3882 ,(2002)
RYUICHIRO NAKAI, SHINGO KAKITA, AKIRA ASAI, SHIGERU CNIBA, SHIRO AKINAGA, TAMIO MIZUKAMI, YOSHINORI YAMASHITA, Chrolactomycin, a novel antitumor antibiotic produced by Streptomyces sp. The Journal of Antibiotics. ,vol. 54, pp. 836- 839 ,(2001) , 10.7164/ANTIBIOTICS.54.836
Takamasa Ueno, Hirotada Takahashi, Masako Oda, Makiko Mizunuma, Akihisa Yokoyama, Yuso Goto, Yoshiyuki Mizushina, Kengo Sakaguchi, Hideya Hayashi, Inhibition of human telomerase by rubromycins: implication of spiroketal system of the compounds as an active moiety. Biochemistry. ,vol. 39, pp. 5995- 6002 ,(2000) , 10.1021/BI992661I
Melanie J Cocco, LA Hanakahi, Michael D Huber, Nancy Maizels, Specific interactions of distamycin with G-quadruplex DNA Nucleic Acids Research. ,vol. 31, pp. 2944- 2951 ,(2003) , 10.1093/NAR/GKG392
N Zaffaroni, S Lualdi, R Villa, D Bellarosa, C Cermele, P Felicetti, C Rossi, L Orlandi, M.G Daidone, Inhibition of telomerase activity by a distamycin derivative: effects on cell proliferation and induction of apoptosis in human cancer cells. European Journal of Cancer. ,vol. 38, pp. 1792- 1801 ,(2002) , 10.1016/S0959-8049(02)00139-9
Shang Li, Julia Crothers, Christopher M. Haqq, Elizabeth H. Blackburn, Cellular and gene expression responses involved in the rapid growth inhibition of human cancer cells by RNA interference-mediated depletion of telomerase RNA. Journal of Biological Chemistry. ,vol. 280, pp. 23709- 23717 ,(2005) , 10.1074/JBC.M502782200
Tony Taldone, Alexander Gozman, Ronnie Maharaj, Gabriela Chiosis, Targeting Hsp90: small-molecule inhibitors and their clinical development Current Opinion in Pharmacology. ,vol. 8, pp. 370- 374 ,(2008) , 10.1016/J.COPH.2008.06.015