Guillain-Barré Syndrome with Optic Neuritis and a Focal Lesion in the Central White Matter Following Epstein-Barr Virus Infection

作者: Jae Young An , Bora Yoon , Joong Seok Kim , In Uk Song , Kwang Soo Lee

DOI: 10.2169/INTERNALMEDICINE.47.1224

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摘要: We report a case of Guillain-Barre syndrome (GBS) accompanied by optic neuritis and central white matter lesion subsequent to Epstein-Barr virus (EBV) infection. A 49-year-old man presented with visual disturbance hemiparesis one week after developing cold-like symptoms. T2- diffusion-weighted brain MRI showed high-signal intensity in the left internal capsule. The patient's acuity improved during steroid pulse therapy, but his progressed quadriparesis. Nerve conduction studies demyelination predominant distal nerve terminals, consistent GBS. Serological testing suggested EBV reinfection. Our findings indicate that EBV-related peripheral can occur simultaneously be successfully treated combination corticosteroids immunoglobulin.

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