Transcriptional regulation of peripheral glial cell differentiation in the embryonic nervous system of Drosophila.
作者： Imke Schmidt , Sigrídur Rut Franzdóttir , Gundula Edenfeld , Floriano Rodrigues , Ariane Zierau
DOI: 10.1002/GLIA.21123
关键词:
摘要: The Drosophila nervous system is ideally suited to study glial cell development and function, because it harbors only relatively few cells, very well conserved during evolution. In the past, enhancer trap studies provided tools allowing cells with a single-cell resolution and, moreover, disclosed surprising molecular heterogeneity among different cells. peripheral in embryo comprises 12 one hemisegment thus offers unique opportunity decipher mechanisms directing development. Here, we focus on transcriptional regulators that have been reported function gliogenesis. To uncover additional regulators, conducted genetic screen report identification of two involved control migration: nejire tango. © 2011 Wiley-Liss, Inc.
sci-hub.se 参考文章(99)
Chris Q. Doe, Akira Chiba, Aloisia Schmid, Clonal analysis of Drosophila embryonic neuroblasts: neural cell types, axon projections and muscle targets. Development. ,vol. 126, pp. 4653- 4689 ,(1999) , 10.1242/DEV.126.21.4653
Paul Badenhorst, Tramtrack controls glial number and identity in the Drosophila embryonic CNS Development. ,vol. 128, pp. 4093- 4101 ,(2001) , 10.1242/DEV.128.20.4093
Hartmut Schmidt, Christof Rickert, Torsten Bossing, Olaf Vef, Joachim Urban, Gerhard M. Technau, The Embryonic Central Nervous System Lineages ofDrosophila melanogaster Developmental Biology. ,vol. 189, pp. 186- 204 ,(1996) , 10.1006/DBIO.1997.8660
Laurent Soustelle, Angela Giangrande, Glial differentiation and the Gcm pathway. Neuron Glia Biology. ,vol. 3, pp. 5- 16 ,(2007) , 10.1017/S1740925X07000464
Yasuhiro Shiga, Miho Tanaka-Matakatsu, Shigeo Hayashi, A nuclear GFP/beta-galactosidase fusion protein as a marker for morphogenesis in living Drosophila Development Growth & Differentiation. ,vol. 38, pp. 99- 106 ,(1996) , 10.1046/J.1440-169X.1996.00012.X
Vanessa J. Auld, Katharine J. Sepp, Conversion of lacZ enhancer trap lines to GAL4 lines using targeted transposition in Drosophila melanogaster. Genetics. ,vol. 151, pp. 1093- 1101 ,(1999) , 10.1093/GENETICS/151.3.1093
Andrea Klaes, Thomas Menne, Angelika Stollewerk, Henrike Scholz, Christian Klämbt, The Ets transcription factors encoded by the Drosophila gene pointed direct glial cell differentiation in the embryonic CNS Cell. ,vol. 78, pp. 149- 160 ,(1994) , 10.1016/0092-8674(94)90581-9
S. Granderath, C. Klambt, C.J. O'Kane, S. Greig, A. Stollewerk, C.S. Goodman, loco encodes an RGS protein required for Drosophila glial differentiation. Development. ,vol. 126, pp. 1781- 1791 ,(1999) , 10.1242/DEV.126.8.1781
T. Awasaki, S.-L. Lai, K. Ito, T. Lee, Organization and Postembryonic Development of Glial Cells in the Adult Central Brain of Drosophila The Journal of Neuroscience. ,vol. 28, pp. 13742- 13753 ,(2008) , 10.1523/JNEUROSCI.4844-08.2008
Rachel L Griffiths, Alicia Hidalgo, Prospero maintains the mitotic potential of glial precursors enabling them to respond to neurons The EMBO Journal. ,vol. 23, pp. 2440- 2450 ,(2004) , 10.1038/SJ.EMBOJ.7600258