Towards Motif Detection in Networks: Frequency Concepts and Flexible Search

作者: Henning Schwöbbermeyer , Falk Schreiber

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摘要: Bioinformatics Center Gatersleben-Halle, Institute ofPlant Genetics and Crop Plant Research Gatersleben,Corrensstrase 3, D-06466 Gatersleben, Germany.{schreibe,schwoebb}@ipk-gatersleben.deAbstract. Network motifs, patterns of local interconnections with po-tential functional properties, are important for the analysis biologicalnetworks. To analyse motifs in networks first step is finding patternsof interest. This paper presents 1) three different concepts de-termination pattern frequency 2) a flexible algorithm to computethese frequencies. The depend onthe reuse network elements. presented finds patternswith highest can be used determine frequencyin directed graphs under consideration these concepts. utility ofthis method demonstrated by applying it real-world data.

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