Tyrosine kinase inhibitor STI571 (Imatinib) cooperates with wild-type p53 on K562 cell line to enhance its proapoptotic effects.
作者： Gianluca Brusa , Manuela Mancini , Fabio Campanini , Alberto Calabrò , Elisa Zuffa
DOI: 10.1159/000087889
关键词:
摘要: In order to ascertain whether p53 has a role in chronic myeloid leukemia hematopoietic progenitor response the innovative tyrosine kinase inhibitor STI571 (Imatinib), we overexpressed wild type (
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