Ga-68-DOTA-TATE PET/CT for Discrimination of Tumors of the Optic Pathway
作者： Annemarie Klingenstein , Alexander R. Haug , Christina Miller , Christoph Hintschich
DOI: 10.3109/01676830.2014.959185
关键词:
摘要: AbstractPurpose: Symptomatic tumors of the optic nerve pathway may endanger vision. They are difficult to classify by imaging alone and biopsy damage visual function. Tumor pathology influences treatment decision a diagnostic tool with high sensitivity specificity would therefore be invaluable. We hypothesized that Ga-68-DOTA-TATE PET/CT help in discriminating as uptake somatostatin is elevated meningiomas.Material Methods: was used examine 13 patients ambiguous, symptomatic lesions for planning. The presence or absence meningioma validated histopathology supplementary work-up.Results: identified 10 meningiomas (en plaque = 1, sheath = 4, sphenoidal = 5) correctly via increased SSTR (somatostatin receptor) expression (mean SUVmax (maximum standardized value) = 14.3 ± 15.4). 3 did not show (SUVma...
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