Kinetics of bimolecular reactions in model bilayers and biological membranes. A critical review.

摘要: The quantitative study of the probability molecular encounters giving rise to a reaction in membranes is challenging discipline. Model systems, model sense that they use bilayers and reactants, have been widely used for this purpose, but methodologies employed analysis results obtained experiments, experimental design, are so disparate concerned experimentalist has difficulty deciding about value each approach. This review intends examine several approaches can be found literature showing, when feasible, weakness, strengths limits application them. There not, far, full validation most promising theories reactions two dimensions, what leaves open large field new research. major challenge resides time range which processes take place, possibilities existing techniques these studies far from exhausted. We also attempts authors quantitatively analyze kinetics biological membranes. Especially field, recently developed microspectroscopies enclose still unexplored potential.