Evaluation of an automated soluble transferrin receptor (sTfR) assay on the Roche Hitachi analyzer and its comparison to two ELISA assays

作者: Christine M. Pfeiffer , James D. Cook , Zuguo Mei , Mary E. Cogswell , Anne C. Looker

DOI: 10.1016/J.CCA.2007.04.008

关键词:

摘要: Abstract Background Soluble transferrin receptor (sTfR) assays are currently not standardized. This hinders data comparison between studies and also affects the use of a recently proposed model to estimate body iron. Methods We evaluated analytical performance fully automated sTfR immunoturbidimetric assay (Roche Diagnostics) compared it with two ELISA (Ramco Laboratories an in-house used in iron model). Results The Roche showed excellent intra- inter-assay precision (CV   0.8); however, values by were on average 30% lower than obtained assays. Conclusions measured can be commonly assay, through regression equations present study.

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